Recomendation from ASEAN Cosmetic Association


The ASEAN Cosmetic Association following the recommendation from Cosmetics Europe and the on-going evaluation of the safety of cosmetic raw materials, recommends that the use of Methylisothiazolinone (MIT) in leave-on skin products, including cosmetic wet wipes, is discontinued.

This recommendation is made in the interest of consumer safety in relation to adverse skin reactions reported by the European Society of Contact Dermatitis.

It is recommended that companies start to implement plans to replace MIT from leave-on skin products (including cosmetic wet wipes) as soon as possible.


MIT is an effective preservative approved under the ASEAN Cosmetic Directive (Annex VI, # 57) for use in leave-on and rinse-off products with a maximum concentration of 0.01% (100ppm).

Recent publications from the dermatology community report an increase in skin reactions to MIT in patients suffering from dermatitis through cosmetic use.

Consumer health and safety is of paramount importance to the cosmetic industry. ACA Scientific and Technical Affairs group has evaluated the scientific data available and concluded that, despite the absence of similar reports from ASEAN, the industry should be pro-active and discontinue the use of MIT in leave-on products including wet wipes.